Find hotels in Southeast Missouri, MO from CA $78
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Our top choices for Southeast Missouri hotels
Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,002 reviews)
"The breakfast and nightly gathering makes this location a fantastic value and will be our choice of stops when heading south again!"
William
The price is CA $121
CA $128 total
includes taxes & fees
Jun 28 - Jun 29
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (203 reviews)
"The room was clean, the staff was extremely helpful with our check in!"
Travis
The price is CA $131
CA $148 total
includes taxes & fees
Jul 9 - Jul 10
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,005 reviews)
"Wonderful room and food offerings were extra thoughtful."
Jonna
The price is CA $145
CA $163 total
includes taxes & fees
Jul 7 - Jul 8
Hampton Inn Poplar Bluff
Hampton Inn Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (879 reviews)
"Nice quiet overnight stay."
Tammy
The price is CA $155
CA $174 total
includes taxes & fees
Jul 12 - Jul 13
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHGFestus
9.4 out of 10, Exceptional, (738 reviews)
"Great stay."
Delos
The price is CA $167
CA $191 total
includes taxes & fees
Jul 5 - Jul 6
Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
9.6 out of 10, Exceptional, (140 reviews)
"This is a clean, quiet, well designed hotel."
Kendra
The price is CA $138
CA $158 total
includes taxes & fees
Jul 3 - Jul 4
Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (924 reviews)
"Hotel Staff was very friendly!"
Alice
The price is CA $162
CA $183 total
includes taxes & fees
Jul 10 - Jul 11
Super 8 by Wyndham Perryville
Super 8 by Wyndham PerryvillePerryville
8.4 out of 10, Very good, (1,000 reviews)
"Enjoyed our stay "
Cynthia
The price is CA $100
CA $115 total
includes taxes & fees
Jul 9 - Jul 10
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott BonvoyFrench Village
9.8 out of 10, Exceptional, (79 reviews)
"The Experience was amazing and we enjoyed the views and the firepit!"
Kenzia
The price is CA $155
CA $228 total
includes taxes & fees
Jul 9 - Jul 10
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
La Quinta Inn & Suites by Wyndham Festus - St. Louis SouthFestus
7.8 out of 10, Good, (1,001 reviews)
"Clean room, check in was easy. It was a good stopover for 1 night."
Nancy
The price is CA $119
CA $137 total
includes taxes & fees
Jul 9 - Jul 10
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.6 out of 10, Exceptional, (1,002 reviews)
"Great place!"
Jennifer
The price is CA $158
CA $181 total
includes taxes & fees
Jul 9 - Jul 10
Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (96 reviews)
"Great stay, kind staff, very clean property."
Joni
The price is CA $156
CA $177 total
includes taxes & fees
Jul 9 - Jul 10
Crown Pointe Lodge, BW Signature Collection
Crown Pointe Lodge, BW Signature CollectionFarmington
9.0 out of 10, Wonderful, (635 reviews)
"Excellent staff and location was nice and quiet
"
Colleen
The price is CA $169
CA $184 total
includes taxes & fees
Jun 28 - Jun 29
The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (610 reviews)
"Always a great place to stay in downtown Cape. Easy access to the local hangouts like Speck Pizza on Broadway."
John
The price is CA $175
CA $197 total
includes taxes & fees
Jun 29 - Jun 30
Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
8.6 out of 10, Excellent, (472 reviews)
"Only stayed one night, no complaints"
Zachary
The price is CA $149
CA $169 total
includes taxes & fees
Jul 26 - Jul 27
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
9.0 out of 10, Wonderful, (787 reviews)
"Beautiful hotel at a very good price."
Sheldon
The price is CA $131
CA $142 total
includes taxes & fees
Jul 9 - Jul 10
Baymont Inn and Suites by Wyndham Farmington, MO
Baymont Inn and Suites by Wyndham Farmington, MOFarmington
8.0 out of 10, Very good, (1,005 reviews)
"It was a great stay"
Daisy
The price is CA $95
CA $103 total
includes taxes & fees
Jul 5 - Jul 6
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
9.0 out of 10, Wonderful, (1,000 reviews)
"Great hotel"
mason
The price is CA $109
CA $123 total
includes taxes & fees
Jul 7 - Jul 8
Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (581 reviews)
"Staff were great at Check in, room was clean, breakfast was good."
Brandi
The price is CA $150
CA $170 total
includes taxes & fees
Jul 9 - Jul 10
Deerfield Inn & Suites Steele Near Blytheville I 55
Deerfield Inn & Suites Steele Near Blytheville I 55Steele
The price is CA $68
CA $79 total
includes taxes & fees
Jun 27 - Jun 28
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Vacation Rentals in Southeast Missouri
Cabin
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott BonvoyFrench Village
9.8 out of 10, Exceptional, (79 reviews)
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Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from Walnut Hollow Lake to K Bridge Recreation Area.
Photo by Bill Dillard
Open Photo by Bill Dillard
Top Southeast Missouri Hotel Reviews
Hampton Inn Poplar Bluff
10/10 Excellent
More cheap stays in Southeast Missouri
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
The price is CA $95 per night from Jul 5 to Jul 6
CA $95
CA $103 total
Jul 5 - Jul 6
includes taxes & fees
8/10 Very good! (1,005 reviews)
Hotels in Southeast Missouri with star rating
4 Star Hotels
2 properties
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